This talk will discuss microarrays of G protein-coupled receptors (GPCRs) and GPCR assays in whole cells using resonant waveguide sensors.  GPCR arrays have the potential to provide selectivity information earlier in drug discovery.   Resonant waveguide sensors enable studies of endogenously expressed GPCRs and therefore provide assay information that is more physiologically relevant relative to conventional assays.

Dr. Joydeep Lahiri joined Corning in 1999 as a senior research scientist in Science & Technology. In 2000, he was appointed group leader, High Sensitivity Assays. In 2002, he was appointed research manager, Biochemical Technologies in the Organic and Biochemical Technologies directorate. He was appointed to his current position as research director, Biochemical Technologies in 2003.

Lahiri was the project leader for the label independent detection project, which has led to the development of the Epic ™ system. He has made several key research contributions, which include the invention of GPCR microarrays and lanthanide-doped microbarcodes. He is a frequently invited speaker, serves as a referee for several publications and participates in NIH study sections. He is the author of over twenty five research publications and holds seven patents.

Lahiri obtained his bachelor’s degree from St. Stephen's College (Delhi), his master’s degree from the Indian Institute of Technology (Kanpur), his doctoral degree in Chemistry from Princeton University and carried out postdoctoral research at Harvard University.